Loretto is located in southern Lawrence County in Middle Tennessee, 90 miles south of Nashville. It is easily reached by interstate 65 to Columbia and U.S. Highway 43 to Loretto. Loretto is six miles north of the Alabama line and is twenty-five miles north of Florence, Alabama.
• On U.S. Highway 43 Interstate 65 is within 40 miles of Loretto.
• Lawrenceburg Municipal Airport is within 17 miles of Loretto.
• Seaboard System Railroad
• Various choices of trucking terminals within 12 miles of Loretto.
• Barge Facilities are located at Florence Alabama on the Tennessee River 26 miles south of Loretto.